Translational Orthopaedic Biomechanics

Advances in orthopaedic medicine almost allow us to take our long-term physical mobility for granted. Still, there remain persistent orthopaedic clinical challenges with no adequate solution. The Translational Orthopaedic Research Group develops fresh clinical concepts in collaboration with the University of Zurich Department of Orthopaedics at the Uniklinik Balgrist.

Understanding implant performance: We have demonstrated that total ankle replacement systems can be highly sensitive to implant component position. Even 2 degrees of “version malalignment” between the components can create regions of concentrated loads that may potential induce surface wear.

  • Analysis of total ankle replacement design

Novel implant development: We have designed an “off-the-shelf” silk graft that may provide a viable alternative to human tendon autograft, reducing the need for a secondary surgical sites to provide needed material.

  • Silk grafts show promise in large animal models

Soft tissue fixation: We have patented several inventions for improved reconstruction of the human anterior cruciate ligament. These devices are co-developed with Balgrist surgeons who lend necessary expertise on surgical approach and technique. Sketch courtesy PD Dr. Mazda Farshad.